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“tumors”

2 referensi ditemukan

JOURNAL PAIinternational2026

The expression of stemness markers in organoids according to histological subtypes of gastric cancer

Yie-Ri Yoo; Kyoungyun Jeong; Jaeun Yoo; Hyun Myong Kim; Ji-Yeon Shin; Min Kyu Kang; Kyoyoung Park; Sa-Hong Kim; Chungyoon Kim; Jeesun Kim; Young Suk Park; Seong-Ho Kong; Hyuk-Joon Lee; Han-Kwang Yang; Do Joong Park · DOAJ Open Access Articles

Purpose Gastric cancer is a heterogeneous disease in which cancer stem cell-associated properties may contribute to tumor heterogeneity and progression. This study aimed to establish paired normal and tumor gastric organoids, characterize stemness-related gene expression, and explore its association with organoid formation. Methods Normal and tumor tissues w…

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26%

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JOURNAL PAIinternational2026

Suppression of MCM2 reduces cancer stem cells and epithelial-mesenchymal transition-related phenotypes in breast cancer cells

Rae-Kwon Kim · DOAJ Open Access Articles

Purpose Minichromosome maintenance protein 2 (MCM2) is a key regulator of DNA replication and has been implicated in tumor progression. While previous studies have demonstrated its role in lung cancer stem cells (CSCs), its role in breast cancer remains unclear. This study aimed to investigate whether MCM2 regulates CSCs and epithelial-mesenchymal transition…

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18%

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