In silico evaluation of 35 novel 3-hydroxy-3-pyrazolyl-1H-indolin-2-one molecules as potential neuropathic pain modulators via voltage-gated sodium channel NaV1.7
Christian Alonso Becerra Rivas; Paola Andrea Cuervo Prado; Fabián Orozco-Lopez · DOAJ Open Access Articles
Neuropathic pain follows nervous system dysfunction or damage, significantly affecting patients’ quality of life. The need for more effective and safer pain management has drawn attention to voltage-gated sodium channels as druggable therapeutic targets in medicinal chemistry, leading to the discovery of various compounds with pharmacological potential, amon…
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