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“heterogeneity”

9 referensi ditemukan

JOURNAL PAIinternational2026

Single-Cell RNA Sequencing Reveals the Heterogeneity and Microenvironment of Temporal Bone Squamous Cell Carcinoma

Wen Lu; Binhong Liao; Zhuangzhuang Li; Yini Li; Jie Li; Linfei Mao; Tianjiao Zhou; Haibo Shi; Dongzhen Yu; Chuan Xu; Zhengnong Chen · DOAJ Open Access Articles

Objectives. Temporal bone squamous cell carcinoma (TBSCC) is the most common subtype of temporal bone malignancy. However, its low incidence, high misdiagnosis rate, and the difficulty of conducting large-scale studies and clinical trials have limited researchers’ understanding of its occurrence and progression, and diagnostic and therapeutic biomarkers rema…

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50%

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REPOSITORY Umuminternational2008

Strength in diversity: enhancing learning in vocationally-orientated, master's level courses

McEwen, L.; Monk, J.; Hay, I.; Kneale, P.; King, H. · White Rose Research Online

Postgraduate education in geography, especially at the Master’s level, is undergoing significant changes in the developed world. There is an expansion of vocationally-oriented degree programmes, increasing recruitment of international students, integration of work place skills, and the engagement of non-traditional postgraduate students as departments respo…

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12%

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REPOSITORY Umuminternational2008

Strength in diversity: enhancing learning in vocationally-orientated, master's level courses

McEwen, L.; Monk, J.; Hay, I.; Kneale, P.; King, H. · White Rose Research Online

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11%

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JOURNAL PAIinternational2026

The expression of stemness markers in organoids according to histological subtypes of gastric cancer

Yie-Ri Yoo; Kyoungyun Jeong; Jaeun Yoo; Hyun Myong Kim; Ji-Yeon Shin; Min Kyu Kang; Kyoyoung Park; Sa-Hong Kim; Chungyoon Kim; Jeesun Kim; Young Suk Park; Seong-Ho Kong; Hyuk-Joon Lee; Han-Kwang Yang; Do Joong Park · DOAJ Open Access Articles

Purpose Gastric cancer is a heterogeneous disease in which cancer stem cell-associated properties may contribute to tumor heterogeneity and progression. This study aimed to establish paired normal and tumor gastric organoids, characterize stemness-related gene expression, and explore its association with organoid formation. Methods Normal and tumor tissues w…

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JOURNAL PAIinternational2026

Phytoplankton community structure responses to episodic summer storms in a temperate coastal ecosystem

H. Chavan; U. Christaki; L. F. Artigas; F. G. Schmitt · DOAJ Open Access Articles

Extreme events potentially modify the physical and biogeochemical environment resulting in dramatic changes in phytoplankton community structure. In this study, the impact of ten well-identified storms on phytoplankton communities was explored in a productive temperate coastal ecosystem, the eastern English Channel (EEC). Our study targeted the summer season…

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JOURNAL Umuminternational2026

From Voluntary to Standardized: The Metamorphosis of Sustainability Reporting under ESRS and ISSB

Dana-Simona GHERAI; Mariana PIPI?; Diana Elisabeta MATICA; Ioan Dan MORAR · DOAJ Open Access Articles

Sustainability reporting has undergone a fundamental structural transformation, shifting from fragmented, voluntary frameworks—long dominated by the Global Reporting Initiative—toward rigorous, standardized, and increasingly mandatory regimes. This evolution has been crystallised by the parallel emergence of two landmark regulatory architectures: the Europea…

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JOURNAL PAIinternational2026

Symbolism in the Poetics of Peter Greenaway

Evallyo Violetta D. · DOAJ Open Access Articles

This article examines symbolism as a structural component of the aesthetics of British film director Peter Greenaway (b. 1942), using his film Drowning by Numbers (1988) and early short films (Water Wrackets, 1975; Making a Splash, 1984; Death in the Seine, 1989). The author departs from the established tradition of interpreting Greenaway’s work exclusively …

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JOURNAL Umuminternational2025

Exploring online search behaviors for information literacy education

Luca Botturi; Loredana Addimando; Martin Hermida; Azza Bouleimen; Chiara Beretta; Silvia Giordano · DOAJ Open Access Articles

Information Literacy education is challenged by an ever-changing and complex environment. The design and development of current and effective Information Literacy education requires a thorough understanding of how young people search information online, which mainly happens with generalist search engines. The present study involved a voluntary sample of 152 …

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JOURNAL PAIinternational2022

Paying for crime: frauds in DPVAT insurance and their impacts on society

Beatriz Peres Lopes; João Vinícius França Carvalho · DOAJ Open Access Articles

The goal of this paper is to assess the weight of fraudulent claim payments of DPVAT insurance by the insurer Líder, a consortium of private insurers who manage this product. Using the Actuarial Credibility Theory, and a official database, the discrepancy between the DPVAT claims ratio and the claims ratios of other private automobile insurance lines of busi…

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