The expression of stemness markers in organoids according to histological subtypes of gastric cancer
Yie-Ri Yoo; Kyoungyun Jeong; Jaeun Yoo; Hyun Myong Kim; Ji-Yeon Shin; Min Kyu Kang; Kyoyoung Park; Sa-Hong Kim; Chungyoon Kim; Jeesun Kim; Young Suk Park; Seong-Ho Kong; Hyuk-Joon Lee; Han-Kwang Yang; Do Joong Park · DOAJ Open Access Articles
Purpose Gastric cancer is a heterogeneous disease in which cancer stem cell-associated properties may contribute to tumor heterogeneity and progression. This study aimed to establish paired normal and tumor gastric organoids, characterize stemness-related gene expression, and explore its association with organoid formation. Methods Normal and tumor tissues w…
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