Single-Cell RNA Sequencing Reveals the Heterogeneity and Microenvironment of Temporal Bone Squamous Cell Carcinoma
Wen Lu; Binhong Liao; Zhuangzhuang Li; Yini Li; Jie Li; Linfei Mao; Tianjiao Zhou; Haibo Shi; Dongzhen Yu; Chuan Xu; Zhengnong Chen · DOAJ Open Access Articles
Objectives. Temporal bone squamous cell carcinoma (TBSCC) is the most common subtype of temporal bone malignancy. However, its low incidence, high misdiagnosis rate, and the difficulty of conducting large-scale studies and clinical trials have limited researchers’ understanding of its occurrence and progression, and diagnostic and therapeutic biomarkers rema…
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